Sorbs2 抗体
Quick Overview for Sorbs2 抗体 (ABIN7119344)
抗原
See all Sorbs2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SORBS2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- sorbin and SH3 domain containing 2
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亚型
- IgG
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应用备注
- IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))
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别名
- SORBS2
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背景
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Synonyms: Sorbin and SH3 domain-containing protein 2|Arg-binding protein 2 (ArgBP2)|Arg/Abl-interacting protein 2|Sorbin|SORBS2|ARGBP2|KIAA0777
Background: Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12(PubMed:18559503). Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.
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基因ID
- 8470
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UniProt
- O94875
抗原
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